SINGLE-CELL RNA SEQUENCING UNCOVERS MOLECULAR MECHANISMS OF INTRAVENOUS IMMUNOGLOBULIN PLUS METHYLPREDNISOLONE IN KAWASAKI DISEASE: ATTENUATED MONOCYTE-DRIVEN INFLAMMATION AND IMPROVED NK CELL CYTOTOXICITY

Single-cell RNA sequencing uncovers molecular mechanisms of intravenous immunoglobulin plus methylprednisolone in Kawasaki disease: attenuated monocyte-driven inflammation and improved NK cell cytotoxicity

IntroductionIntravenous immunoglobulin (IVIG) plus methylprednisolone as initial intensive therapy or additional therapy in Kawasaki disease (KD) has been used in clinical practice.However, its molecular and cellular mechanism is unclear.MethodsWe mens-clothing performed single-cell analysis on 14 peripheral blood mononuclear cell (PBMC) samples ob

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ОЦІНЮВАННЯ ТІНЬОВОЇ ЕКОНОМІКИ ТА ЇЇ ВПЛИВУ НА СОЦІАЛЬНО-ЕКОНОМІЧНИЙ РОЗВИТОК

Тіньова економіка притаманна всім без винятку економічним системам світу.Проте збільшення частки тіньової економіки створює значні перешкоди для зростання в економічній і соціальний сфер�

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Investigation of biophysical mechanisms in gold nanoparticle mediated laser manipulation of cells using a multimodal holographic and fluorescence imaging setup.

Laser based cell manipulation has proven to be a versatile tool in biomedical applications.In this context, combining weakly focused laser pulses and nanostructures, e.g.gold nanoparticles, promises to be useful for high throughput cell manipulation, such as transfection and photothermal therapy.Interactions between laser pulses and gold nanopartic

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Functional Cerebral Venous Anatomy from the Viewpoint of Venous Collaterals Part I, Supratentorial Superficial and Deep Venous System

Abstract Supratentorial veins are divided into superficial and deep venous systems.Most superficial veins drain into the superior sagittal sinus, cavernous sinus, transverse sinus, and inferior sagittal sinuses.Most deep veins drain into the internal cerebral vein, and some drain into the basal vein of Rosenthal, which head toward the great cerebra

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